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John Wayne Casserole is an easy ground beef casserole recipe with a biscuit base and loaded with diced tomatoes, corn, taco seasoning, cream cheese, mozzarella and cheddar.

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John Wayne Casserole is a delicious ground beef and biscuit casserole made with Bisquick.

This simple and flavourful casserole is sure to please the whole family.

This ground beef casserole recipe takes about an hour from start to finish and serves six people.

Printable Recipe Card with a Full List of Ingredients and Instructions is Located at the Bottom of the Post.

Be sure to read through the entire post so that you don't miss out on any important tips and tricks!

To make this casserole, I started by dumping a pound of lean ground beef into a large saute pan over medium-high heat.

I crumbled the ground beef well as it cooked.

Once the ground beef was fully cooked, I drained the grease from the pan.

Then I added some water and taco seasoning to the pan with the ground beef.

I stirred well and left the ground beef and taco seasoning mixture to simmer over medium-high heat for four minutes.

After four minutes, I added some diced onions, two cans of Rotel diced tomatoes and green chilies and some canned corn to the pan with the ground beef.

I stirred well and reduced the heat to low.

Then I poured some Bisquick mix into a large mixing bowl.

I added water to the bowl.

Then I stirred until a sticky dough formed.

I dumped the dough into a greased 9 x 13 inch baking dish and spread it out evenly.

Then I scooped the ground beef mixture on top of the dough and spread it out evenly.

I dumped some whipped chive cream cheese and mayo into a medium mixing bowl.

Then I added some onion powder and salt to the bowl.

I used an electric mixer to cream together the mayo and cream cheese until smooth.

Then I spooned the cream cheese mixture over the ground beef layer in the baking dish and spread it out as evenly as possible.

I sprinkled some shredded mozzarella and cheddar cheese on top of the cream cheese mixture.

Then I placed the dish in the oven and baked it for 40 minutes.

After 40 minutes I removed the casserole from the oven and left it to sit for a few minutes before slicing and serving.

This cheesy ground beef and biscuit casserole is the perfect comfort food.

The Rotel and taco seasoning give this dish a bit of a kick but it's not overly spicy.

If you are looking for a tasty casserole recipe using ground beef, then you need to try this John Wayne Casserole!

More Easy Ground Beef Casserole Recipes You'll Love…

PRINTABLE VERSION OF THE RECIPE CAN BE FOUND AT THE BOTTOM OF THE PAGE

Ingredients You'll Need to Make This John Wayne Casserole:

• 1 lb lean ground beef
• 1 cup water
• 1 oz taco seasoning
• 1 cup diced yellow onion
• 20 oz Rotel diced tomatoes and green chilies, drained
• 12 oz canned corn, drained

Biscuit Layer

• 3 cups Bisquick mix
• 1 cup water

Topping

• 7.5 oz Philadelphia whipped chive cream cheese
• 1/2 cup mayo
• 1 tbsp onion powder
• 1/2 tsp salt
• 2 cups shredded mozzarella and cheddar cheese blend

How to Make John Wayne Casserole:

1. Preheat oven to 325F.
2. Dump ground beef into a large saute pan over medium-high heat.
3. Crumble ground beef well as it cooks.
4. Once the ground beef is fully cooked, drain the grease from the pan.
5. Add the water and taco seasoning to the pan with the ground beef.
6. Stir well and leave to simmer over medium-high heat for 4 minutes.
7. Add the diced onions, Rotel and corn to the pan.
8. Stir well and reduce the heat to low.
9. Dump the Bisquick mix and water into a mixing bowl.
10. Stir until a sticky dough forms.
11. Dump the dough into the bottom of a greased 9 x 13 inch baking dish and spread it out evenly.
12. Dump the ground beef mixture on top of the dough and spread it out evenly.
13. Dump the cream cheese, mayo, onion powder and salt into a mixing bowl and cream together with an electric mixer until smooth.
14. Spoon the cream cheese mixture on top of the ground beef mixture in the baking dish and spread it out as evenly as possible.
15. Sprinkle the shredded mozzarella and cheddar cheese on top.
16. Place the dish in the oven and bake for 40 minutes.
17. After 40 minutes remove the casserole from the oven and allow it to sit for a few minutes before slicing and serving.
18. Enjoy!

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Prep Time 30 minutes

Cook Time 40 minutes

Total Time 1 hour 10 minutes

Instructions

1. Preheat oven to 325F.
2. Dump ground beef into a large saute pan over medium-high heat.
3. Crumble ground beef well as it cooks.
4. Once the ground beef is fully cooked, drain the grease from the pan.
5. Add the water and taco seasoning to the pan with the ground beef.
6. Stir well and leave to simmer over medium-high heat for 4 minutes.
7. Add the diced onions, Rotel and corn to the pan.
8. Stir well and reduce the heat to low.
9. Dump the Bisquick mix and water into a mixing bowl.
10. Stir until a sticky dough forms.
11. Dump the dough into the bottom of a greased 9 x 13 inch baking dish and spread it out evenly.
12. Dump the ground beef mixture on top of the dough and spread it out evenly.
13. Dump the cream cheese, mayo, onion powder and salt into a mixing bowl and cream together with an electric mixer until smooth.
14. Spoon the cream cheese mixture on top of the ground beef mixture in the baking dish and spread it out as evenly as possible.
15. Sprinkle the shredded mozzarella and cheddar cheese on top.
16. Place the dish in the oven and bake for 40 minutes.
17. After 40 minutes remove the casserole from the oven and allow it to sit for a few minutes before slicing and serving.
18. Enjoy!

Nutrition Information:

Yield:

6

Serving Size:

1
Amount Per Serving: Calories: 848 Total Fat: 50g Saturated Fat: 18g Trans Fat: 1g Unsaturated Fat: 27g Cholesterol: 127mg Sodium: 2298mg Carbohydrates: 62g Fiber: 4g Sugar: 14g Protein: 39g

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